Ergothioneine Powder

Ergothioneine powder is a water-soluble, sulfur-containing amino acid derivative used in cosmetic formulations and researched for its antioxidant properties. CHEN LANG BIO TECH manufactures and supplies high-purity L-ergothioneine (CAS 497-30-3) for cosmetic ingredient distributors, formulation laboratories, and manufacturers developing specialized antioxidant products.

 

Our L-ergothioneine is available as a white powder with a purity specification of ≥98%. We support commercial ingredient sourcing with batch-specific quality documentation, flexible packaging, sample evaluation, and international shipping arrangements. Customers can request a Certificate of Analysis (COA), technical information, and a quotation based on their required quantity.

 

Ergothioneine Powder Specifications

 

The following specifications summarize our current commercial product. Final acceptance criteria should be confirmed against the latest product specification and batch COA.

 

Parameter	Specification
Product Name	L-Ergothioneine
INCI Name	Ergothioneine
CAS Number	497-30-3
Molecular Formula	C₉H₁₅N₃O₂S
Molecular Weight	229.30 g/mol
Appearance	White powder
Purity	≥98%
Solubility	Water soluble
Manufacturing Process	Enzyme-catalyzed production
Standard Packaging	1–5 kg/aluminum foil bag; 25 kg/paper drum
MOQ	1 kg
Documentation	COA, TDS, SDS upon request
Application Areas	Cosmetic formulations; nutraceutical and functional ingredient development, subject to applicable regulations

 

For buyers evaluating L-ergothioneine powder, the most important specifications include identity, assay, appearance, moisture content, and impurity limits. Additional quality requirements may depend on the intended application and destination market.

 

We recommend reviewing the current COA before approving a material for commercial production.

 

What Is Ergothioneine Powder?

 

Ergothioneine is a naturally occurring sulfur-containing derivative of histidine. It is synthesized by certain microorganisms, including fungi and bacteria, and is present in foods such as mushrooms.

 

Unlike many conventional antioxidant ingredients, ergothioneine has a distinctive sulfur-containing chemical structure and is associated with a specific cellular transport system known as OCTN1, encoded by the SLC22A4 gene.

 

Its antioxidant behavior has been investigated in relation to reactive oxygen species, oxidative stress, and cellular protection. These properties have attracted interest from researchers and cosmetic formulators developing products intended to support skin condition and appearance.

 

Commercial ergothioneine raw material is supplied in a concentrated powder form, allowing manufacturers to incorporate the ingredient into appropriately designed formulations without relying on naturally occurring concentrations in botanical or fungal extracts.

 

The finished ingredient's identity, purity, and impurity profile are more relevant to commercial procurement than broad claims about antioxidant activity alone.

 

L-Ergothioneine Manufacturing Process

 

Manufacturing consistency is an important consideration when sourcing specialty amino acid derivatives. Differences in production technology, purification efficiency, and process control can affect ingredient quality and batch reproducibility.

 

►Enzyme-Catalyzed Production

 

Our production process uses enzyme-catalytic technology to manufacture L-ergothioneine under controlled processing conditions.

 

Enzymatic production offers a route for selective biochemical conversion. However, the actual process performance depends on enzyme activity, reaction conditions, substrate quality, and downstream purification.

 

As an ergothioneine manufacturer, we focus on maintaining consistent production conditions and controlling the quality of the finished ingredient.

 

The manufacturing process involves controlled biochemical conversion followed by downstream separation, purification, and preparation of the final powder.

 

►Purification and Batch Consistency

 

Following the conversion stage, the material undergoes purification to reduce process-related impurities and obtain the required product quality.

 

The purified ingredient is then processed into powder and evaluated against the applicable batch-release specification.

 

For commercial buyers, batch consistency is particularly important when an ingredient is used in repeated production runs. Changes in assay, moisture, or impurity profile may affect material acceptance and formulation performance.

 

Our technical team can discuss product specifications and manufacturing-related documentation with customers during supplier qualification.

 

Quality Control and Analytical Testing

 

A reliable supply of high-purity ergothioneine requires more than a stated assay value. Buyers should also review the analytical method, identification results, impurity limits, and relevant safety-related specifications.

 

Identity, Purity and Batch Release

 

Our quality control system includes laboratory testing and batch evaluation according to the applicable product specification.

 

Depending on the agreed testing scope, relevant parameters may include:

 

•Identification and assay

 

•Appearance and physical characteristics

 

•Moisture or loss on drying

 

•Heavy metal limits

 

•Microbiological quality

 

•Process-related impurities

 

Chromatographic analysis, including HPLC where specified, can be used to assess ingredient purity. The analytical method and acceptance limits should be confirmed in the current specification.

 

Customers requesting ergothioneine powder COA documentation can review the reported batch results before shipment.

 

Documentation for Ingredient Buyers

 

We support ingredient evaluation and purchasing decisions with available technical documentation, including the Certificate of Analysis, Technical Data Sheet, and Safety Data Sheet.

 

Additional documentation requirements can be discussed according to the intended market, order quantity, and customer qualification procedure.

 

A COA confirms the reported results for a particular batch; it should not be interpreted as automatic regulatory approval for every intended use.

 

Ergothioneine Powder Applications

 

Ergothioneine has attracted commercial interest because of its antioxidant-related properties and compatibility with selected formulation systems.

 

The appropriate application depends on the finished product category, formulation requirements, ingredient grade, and applicable regulations.

 

•Ergothioneine for Cosmetic Formulations

 

One of the principal applications of ergothioneine cosmetic ingredient materials is the development of antioxidant-focused skincare formulations.

 

Ergothioneine can be evaluated for incorporation into products such as facial serums, moisturizers, eye creams, essences, and other leave-on cosmetic formulations.

 

Its water solubility makes it relevant to aqueous systems and water-containing emulsions, although compatibility should be verified in the complete formulation.

 

For cosmetic manufacturers, important development considerations include ingredient concentration, pH compatibility, processing temperature, color stability, and interactions with other formulation components.

 

Ergothioneine may be used in formulations positioned around antioxidant care and the visible signs of skin aging, provided the finished-product claims are supported by appropriate evidence.

 

It should not be presented as a treatment for skin diseases or as a replacement for approved UV filters in sunscreen products.

 

•Ergothioneine for Nutraceutical Formulations

 

Ergothioneine is also being investigated as an ingredient for nutritional product development.

 

Manufacturers evaluating ergothioneine for supplements may consider powder-filled capsules, tablets, or other solid dosage formats where the ingredient is legally permitted.

 

In this application, ingredient identity, purity, contaminant limits, and manufacturing consistency are particularly important.

 

Regulatory status must be assessed separately for each target market. Permission to use ergothioneine in a cosmetic formulation does not automatically establish its suitability for dietary supplements or foods.

 

•Functional Food and Beverage Development

 

Water-soluble ingredients may be of interest to developers of functional beverage and powdered nutrition products.

 

Ergothioneine can be investigated for formulation compatibility in aqueous systems, but developers should evaluate dissolution behavior, sensory effects, stability, and interactions with other ingredients under actual processing conditions.

 

Any proposed food or beverage use must comply with the relevant authorization, ingredient specifications, and permitted conditions of use in the destination market.

 

Solubility, Stability and Formulation Considerations

 

Ergothioneine powder solubility is an important technical consideration for formulators selecting antioxidant ingredients.

 

L-Ergothioneine is soluble in water, making it suitable for evaluation in water-based systems. However, solubility alone does not establish compatibility with every formulation.

 

♦Water Solubility and Incorporation

 

For aqueous formulations, ergothioneine may be dissolved in a suitable water phase before incorporation into the finished product.

 

The appropriate addition procedure depends on the target concentration, solvent composition, processing temperature, and other formulation ingredients.

 

Manufacturers should verify complete dissolution and assess the physical stability of the finished product during development.

 

♦pH, Temperature and Storage

 

Although ergothioneine has been investigated for its chemical stability, finished-formulation performance depends on the surrounding conditions.

 

Formulators should evaluate the effects of pH, temperature, light exposure, oxygen, and interactions with other ingredients.

 

A stability profile established for the raw material should not be assumed to apply unchanged to a finished serum, cream, or beverage.

 

For commercial development, we recommend conducting formulation-specific compatibility and stability testing before scale-up.

 

Bulk Packaging, MOQ and Global Supply

 

We provide bulk ergothioneine powder for manufacturers and ingredient distributors requiring reliable commercial quantities.

 

Our standard packaging options include:

 

1–5 kg/aluminum foil bag: Suitable for smaller commercial orders and formulation development.

 

25 kg/paper drum: Suitable for larger production requirements.

 

Packaging is designed to protect the material during handling, storage, and international transportation. Customers should keep containers tightly closed and follow the storage instructions in the current product documentation.

 

Our standard minimum order quantity is 1 kg, subject to stock and order confirmation.

 

For available inventory, shipments can generally be arranged within 2–3 working days after order confirmation. Larger orders may require a production schedule based on quantity and current capacity.

 

We also support sample requests for laboratory evaluation before commercial procurement.

 

Why Choose CHEN LANG BIO TECH?

 

Selecting an ergothioneine powder supplier involves evaluating technical capability, product consistency, documentation, and the ability to support repeat orders.

 

CHEN LANG BIO TECH combines ingredient manufacturing experience with laboratory testing and international raw material supply.

 

Our team works with cosmetic manufacturers, formulation laboratories, contract manufacturers, and ingredient distributors requiring technical information and commercial purchasing support.

 

We provide product documentation, flexible packaging arrangements, and communication throughout the sampling, qualification, and ordering process.

 

For customers planning recurring purchases, we can discuss batch requirements, projected quantities, and supply schedules to support procurement planning.

 

Our objective is to provide clearly specified raw materials supported by practical technical and commercial service.

 

Frequently Asked Questions

 

What purity grades of L-ergothioneine do you supply?

 

Our current published specification is ≥98% purity. Customers requiring a different assay grade should contact our sales team to confirm availability and request the corresponding product specification and COA.

 

Is ergothioneine powder soluble in water?

 

Yes. L-Ergothioneine is water soluble and can be evaluated for use in aqueous formulations. Actual dissolution behavior depends on concentration, temperature, and formulation composition.

 

How is your ergothioneine manufactured?

 

Our current production description identifies an enzyme-catalyzed manufacturing process. Customers requiring additional process information for supplier qualification can discuss available documentation with our technical team.

 

Can you provide a COA and samples?

 

Yes. Batch-specific COA documentation and samples can be requested for quality evaluation. Sample availability, quantity, and shipping arrangements should be confirmed before dispatch.

 

What is the MOQ and lead time for bulk orders?

 

Our standard MOQ is 1 kg. In-stock material can generally be dispatched within 2–3 working days after order confirmation. Lead times for larger orders depend on stock availability and production scheduling.

 

Request Ergothioneine Powder Pricing and Samples

 

If you are sourcing ergothioneine powder for cosmetic manufacturing, ingredient distribution, or an eligible nutritional application, contact CHEN LANG BIO TECH for product specifications and commercial supply information.

 

To receive an ergothioneine powder price quotation, please provide your required purity, order quantity, destination country, and intended application.

 

Our sales team can assist with sample requests, available documentation, packaging options, and shipment arrangements.

 

XI AN CHEN LANG BIO TECH CO., LTD

 

Email: admin@chenlangbio.com

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Phone: +86-17782478823

 

Contact us to request a COA, evaluate a sample, or discuss your next bulk ingredient order.